News & Insight

News
A network approach reveals roles for cancer stem cells in cancer promotion
Q&A with Professor Allan Balmain and Dr Mark Taylor on new findings from the PROMINENT team, tackling our Normal Phenotypes challenge
We talked to team PROMINENT members Professor Allan Balmain and Dr Mark Taylor from the University of California San Francisco about their latest paper ‘Stem-cell states converge in multi-stage cutaneous squamous cell carcinoma development…
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News
Global team uncovers genomic secrets behind varied incidence in kidney cancer rates
In a landmark paper published today (1 May, 2024) by the Mutographs team in Nature, they identify new mutational signatures at play in the…
News
Five new teams selected to take on cancer’s toughest challenges
Today we’re excited to announce the five new global teams that have been selected to each receive up to $25m in Cancer Grand Challenges funding over…
Blog
Embedding patient advocacy within a discovery science initiative
As we look towards announcing our new teams on 6 March, we reflect with former members of the Cancer Grand Challenges Advocacy Panel on the role the…
Blog
A holistic approach to cancer research: bringing future research leaders together with patient advocates
Last month we held our annual Future Leaders Conference in Lisbon. As well as being a time for early career researchers from across our funded teams…

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Ed Boyden
News
News from the IMAXT team: Expansion Sequencing technology
In a new Science paper, members of the Cancer Grand Challenges IMAXT team announce ExSeq – new technology that can create nanoscale-resolution genomic maps of tumour samples by combining the expansion of biological…
Ed Harlow
Blog
The Challenges: Ed Harlow shares his thoughts on the inflammation challenge
In October, Cancer Grand Challenges posed 9 new quests for the research community, each with the potential to contribute major advances to the way we think about and deal with the burden of cancer. Through our new blog…
Nic Jones 3
Blog
The Challenges: Professor Nic Jones on dormancy
In October, we posed 9 new challenges to the research community, each with the potential to change the way we think about cancer. Through our new blog series, members of our Cancer Grand Challenges Scientific Committee …
Metabolic imaging of Kras mutant intestinal epithelium
People
Multidisciplinary collaboration driving new discoveries: uncovering the role of SLC7A5 in KRAS-driven colorectal cancer
New findings from the Rosetta team have identified the antiporter SLC7A5 as a target for KRAS-driven colorectal cancer. We spoke with some of the co-authors to get their take on how a multidisciplinary team approach…
Professor Karen Vousden
Blog
The Challenges: Professor Karen Vousden on the normal phenotypes challenge
In October, we posed 9 new challenges to the research community, each with the potential to change the way we think about cancer. Through our new blog series, members of our Cancer Grand Challenges Scientific Committee …
Don Inger, STORMing Cancer team
News
STORMing Cancer's Professor Don Ingber receives prestigious Wilbur Cross Medal
Congratulations to STORMing Cancer’s Professor Don Ingber for winning Yale University’s Wilbur Cross Medal for Alumni Achievement.   Don pioneered the field of mechanobiology when he first made the link between the…
Rene Bernards challenge series header
Blog
The Challenges: Professor René Bernards on the senescence challenge
In October, we posed 9 new challenges to the research community, each with the potential to change the way we think about cancer. Through our new blog series, members of our Cancer Grand Challenges Scientific Committee …
Iain Foulkes and Ned Sharpless
Coverage
AACR Cancer Discovery In Focus: embarking on a new era of discovery
In a commentary article for AACR Cancer Discovery In Focus, Dr Iain Foulkes and Dr Ned Sharpless discuss the 9 Cancer Grand Challenges open for application from now until 22 April 2021. “Making progress in these fields…
Crystall McKall
Blog
The Challenges: Professor Crystal Mackall on the solid tumours in children challenge
In October, we posed 9 new challenges to the research community, each with the potential to change the way we think about cancer. Through our new blog series, members of our Cancer Grand Challenges Scientific Committee…