News & Insight

News
A network approach reveals roles for cancer stem cells in cancer promotion
Q&A with Professor Allan Balmain and Dr Mark Taylor on new findings from the PROMINENT team, tackling our Normal Phenotypes challenge
We talked to team PROMINENT members Professor Allan Balmain and Dr Mark Taylor from the University of California San Francisco about their latest paper ‘Stem-cell states converge in multi-stage cutaneous squamous cell carcinoma development…

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In a landmark paper published today (1 May, 2024) by the Mutographs team in Nature, they identify new mutational signatures at play in the…
News
Today we’re excited to announce the five new global teams that have been selected to each receive up to $25m in Cancer Grand Challenges funding over…
Blog
As we look towards announcing our new teams on 6 March, we reflect with former members of the Cancer Grand Challenges Advocacy Panel on the role the…
Blog
Last month we held our annual Future Leaders Conference in Lisbon. As well as being a time for early career researchers from across our funded teams…

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News
In October 2021 we held our first Future Leaders Conference, a chance for the early career members of our community to come together virtually, discuss their work and focus on professional development.  The event was …
News
Cancers in different parts of the body use unique strategies to avoid attack by the immune system, according to a new study from the Cancer Grand Challenges SPECIFICANCER team and collaborators. The findings also…
News
How do tumours avoid attack from the immune system? For some head and neck cancers, the answer lies on the short, p, arm of chromosome 9 – findings from the Cancer Grand Challenges SPECIFICANCER team which could lead…
News
We (virtually) sat down with John Marioni, new collaborator on the Cancer Grand Challenges IMAXT programme to find out more about his work. John is a senior group leader at the Cancer Research UK Cambridge Institute,…
News
OPTIMISTICC’s Cindy Sears is a clinician scientist at Johns Hopkins University School of Medicine and an expert in infectious disease and colorectal cancer. In July, Cindy and the team shared a new mouse model which…
News
On the surface, astronomy has little overlap with bioinformatics, mutational analysis and other areas of cancer biology. But, as described by IMAXT’s Nic Walton, an astronomer based at the University of Cambridge, there…
Video
Sir Mike Stratton, based at the Wellcome Sanger Institute in Cambridge, UK, leads the Cancer Grand Challenges Mutographs team. Mutographs unites genomicists with epidemiologists, building on recent developments in…
News
Earlier this year, COSMIC - the world's largest and most comprehensive resource for exploring somatic mutations in cancer - celebrated the curation of its 10 millionth mutation.  PhD student Ellie Dunstone discusses…
Video
Johanna Joyce is co-investigator of the Cancer Grand Challenges IMAXT team, based in Lausanne, Switzerland.   We caught up with Johanna to learn how diverse, global collaboration is helping to unlock new information…