News & Insight

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A network approach reveals roles for cancer stem cells in cancer promotion
Q&A with Professor Allan Balmain and Dr Mark Taylor on new findings from the PROMINENT team, tackling our Normal Phenotypes challenge
We talked to team PROMINENT members Professor Allan Balmain and Dr Mark Taylor from the University of California San Francisco about their latest paper ‘Stem-cell states converge in multi-stage cutaneous squamous cell carcinoma development…
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Global team uncovers genomic secrets behind varied incidence in kidney cancer rates
In a landmark paper published today (1 May, 2024) by the Mutographs team in Nature, they identify new mutational signatures at play in the…
News
Five new teams selected to take on cancer’s toughest challenges
Today we’re excited to announce the five new global teams that have been selected to each receive up to $25m in Cancer Grand Challenges funding over…
Blog
Embedding patient advocacy within a discovery science initiative
As we look towards announcing our new teams on 6 March, we reflect with former members of the Cancer Grand Challenges Advocacy Panel on the role the…
Blog
A holistic approach to cancer research: bringing future research leaders together with patient advocates
Last month we held our annual Future Leaders Conference in Lisbon. As well as being a time for early career researchers from across our funded teams…

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"NexTGen represents crucial and overdue work” Sara Wakeling, NexTGen team advocate and CEO and co-founder of Alice's Arc
News
Targeting vulnerabilities of childhood cancers
Cancer is the second leading cause of death among children and adolescents worldwide. Yet, despite progress in understanding the biology of many childhood cancers, treatments, particularly for solid tumours, have…
2022/23 Discover: A year of scientific creativity
News
Discover: a year of scientific creativity 2023
Today we launch Discover: a year of scientific creativity – our annual progress magazineWe are excited to launch our annual progress magazine, Discover: a year of scientific creativity. Discover celebrates how the…
"Being a part of Cancer Grand Challenges is truly a unique experience" Amy Brigham and Women's Hospital and team SPECIFICANCER
Blog
"Being a part of Cancer Grand Challenges is truly a unique experience"
In November 2022, Cancer Grand Challenges held its first in-person Future Leaders Conference in Barcelona, providing an opportunity for early-career researchers worldwide to connect, network and spark new scientific…
"I really believe the way we enable research through Cancer Grand Challenges will ultimately make a difference for people with cancer" Gemma Balmer-Kemp, head of research, Cancer Grand Challenges
Blog
The multifaceted approach of Cancer Grand Challenges research
Cancer Grand Challenges research covers a broad spectrum of areas and disciplines, with teams generating novel insights at each stage of the research pipeline. Here, Gemma Balmer-Kemp, head of research at Cancer Grand…
Spotlight on the new Cancer Grand Challenges teams
Blog
Spotlight on the new Cancer Grand Challenges teams
Cancer Grand Challenges awarded grants to four teams –CANCAN, PROMINENT, eDyNAmiC and NexTGen – in its third round of funding in 2022. Charles Swanton, a member of the Cancer Grand Challenges Scientific Committee,…
eDyNAmiC
News
Novel insights into the role of ecDNA in the cancerous transition of Barrett's oesophagus
Lorenzo de la Rica, Research Programme Manager at Cancer Grand Challenges, provides his insights on the importance of the latest paper from the Cancer Grand Challenges eDyNAmiC team, tackling the extrachromosomal DNA…
A scanning electron micrograph of cancer cells in the intestine STEVE GSCHMEISSNER/SCIENCE PHOTO LIBRARY
Coverage
Cancer mystery as cases rise among younger people around the world
When it comes to cancer research, we regularly hear good news about the number of people benefiting from advances in treatment. But there is one bad news story about the condition that gets little attention. For three…
Nine new challenges
Blog
Announcing nine of cancer’s toughest challenges with up to $25m funding for global research teams
Today we announce nine new Cancer Grand Challenges, for which Expressions of Interest are now open. These are the obstacles that continue to impede progress against cancer and that no one scientist, institution or…
CGC new Scientific Committ
Blog
Introducing our new Scientific Committee members
We are pleased to welcome five new members to the Cancer Grand Challenges Scientific Committee: Professor Michael Hall (University of Basel), Professor Sherene Loi (Peter MacCallum Cancer Center), Professor KJ Patel (…